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Michael Didriksen Selected Research

3- (1- (2- (1- acetyl- 2,3- dihydro- 1H- indol- 3- yl)ethyl)- 3,6- dihydro- 2H- pyridin- 4- yl)- 6- chloro- 1H- indole

11/2007Lu 35-138 ((+)-(S)-3-{1-[2-(1-acetyl-2,3-dihydro-1H-indol-3-yl)ethyl]-3,6-dihydro-2H-pyridin-4-yl}-6-chloro-1H-indole), a dopamine D4 receptor antagonist and serotonin reuptake inhibitor: characterisation of its in vitro profile and pre-clinical antipsychotic potential.

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Michael Didriksen Research Topics

Disease

14Schizophrenia (Dementia Praecox)
01/2020 - 11/2004
4Cognitive Dysfunction
11/2018 - 08/2006
3Psychotic Disorders (Schizoaffective Disorder)
06/2017 - 10/2011
2Chromosome 15q13.3 Microdeletion Syndrome
01/2019 - 01/2016
2Mental Disorders (Mental Disorder)
01/2017 - 09/2015
1Neurobehavioral Manifestations
01/2020
1DiGeorge Syndrome (Syndrome, DiGeorge)
11/2018
11.35-Mb Chromosome 1q21.1 Deletion Syndrome
11/2017
1Sleep Deprivation
06/2017
1Mania (Manias)
06/2017
1Bipolar Disorder (Manic Depressive Psychosis)
06/2017
1Autistic Disorder (Autism)
09/2015
1Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
09/2015
1Vaccinia
10/2011
1Parkinson Disease (Parkinson's Disease)
04/2010
1Catalepsy
11/2007
1Dystonia (Limb Dystonia)
11/2007
1Memory Disorders (Memory Loss)
08/2007
1Hypersensitivity (Allergy)
01/2006

Drug/Important Bio-Agent (IBA)

6Antipsychotic Agents (Antipsychotics)IBA
06/2017 - 01/2006
4Clozapine (Clozaril)FDA LinkGeneric
01/2020 - 06/2006
3Amphetamine (Amfetamine)FDA LinkGeneric
01/2019 - 11/2004
3Biological ProductsIBA
01/2019 - 09/2015
3Dopamine (Intropin)FDA LinkGeneric
11/2017 - 11/2004
2ChromatinIBA
01/2020 - 01/2017
2ParvalbuminsIBA
01/2020 - 01/2006
2Transcription Factor 4IBA
01/2017 - 10/2011
2gamma-Aminobutyric Acid (GABA)IBA
06/2012 - 01/2006
2sertindole (Serdolect)IBA
08/2007 - 08/2006
2Phencyclidine (Angel Dust)IBA
08/2007 - 01/2006
2N-Methylaspartate (NMDA)IBA
08/2007 - 06/2006
1Proteins (Proteins, Gene)FDA Link
01/2019
1Pharmaceutical PreparationsIBA
01/2019
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
11/2018
1Biomarkers (Surrogate Marker)IBA
11/2018
1Antidepressive Agents (Antidepressants)IBA
06/2017
1Serotonin (5 Hydroxytryptamine)IBA
06/2017
1asenapineFDA Link
06/2017
1RNA (Ribonucleic Acid)IBA
01/2017
1Carrier Proteins (Binding Protein)IBA
01/2017
1CalciumIBA
01/2017
1Cholinergic Agents (Cholinergics)IBA
01/2017
1ElementsIBA
01/2017
1Adenosine Monophosphate (AMP)IBA
01/2017
1Histones (Histone)IBA
01/2017
1Calcium Channels (Calcium Channel)IBA
01/2017
1PhosphoproteinsIBA
01/2017
1Dopamine Receptors (Dopamine Receptor)IBA
01/2017
1Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA
01/2017
1Acetylcholine (Acetylcholine Chloride)FDA Link
01/2016
1Aminobutyrates (Aminobutyric Acid)IBA
06/2012
13- bromo- 10- difluoromethyl- 9H- imidazo(1,5- a)(1,2,4)triazolo(1,5- d)(1,4)benzodiazepineIBA
06/2012
1Phosphotransferases (Kinase)IBA
10/2011
1NeurograninIBA
10/2011
1Neurotransmitter Agents (Neurotransmitter)IBA
10/2011
11- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
04/2010
1Chlorpromazine (Thorazine)FDA Link
09/2008
13- (1- (2- (1- acetyl- 2,3- dihydro- 1H- indol- 3- yl)ethyl)- 3,6- dihydro- 2H- pyridin- 4- yl)- 6- chloro- 1H- indoleIBA
11/2007
1Risperidone (Risperdal Consta)FDA LinkGeneric
08/2007
1Olanzapine (Zyprexa)FDA Link
08/2006
1Serine (L-Serine)FDA Link
06/2006
1IsoxazolesIBA
06/2006
1propionic acid (potassium propionate)IBA
06/2006
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
06/2006
1Glycine (Aminoacetic Acid)FDA LinkGeneric
06/2006
1AMPA Receptors (AMPA Receptor)IBA
06/2006
1Cycloserine (Seromycin)FDA Link
06/2006
1methylazoxymethanolIBA
01/2006
1Calcium-Binding ProteinsIBA
01/2006

Therapy/Procedure

1Therapeutics
09/2015